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NotesBiology HLTopic 1.3Cells as the smallest units of self-sustaining life
Back to Biology HL Topics
1.3.24 min read

Cells as the smallest units of self-sustaining life (Biology HL)

IB Biology · Unit 1

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Contents

  1. 1Life is cellular — and it had to start somehow
  2. 2Living or non-living? Why viruses are not alive
  3. 3Exam-style question (step by step)
The big idea: The cell is the smallest unit of life that can sustain itself: it can take in materials, release energy, grow and reproduce on its own.

All life is cellular, but cells had a start

  • Every living thing we know of is made of cells: bacteria are single cells, and a whale is trillions of them.
  • There is no smaller free-living unit than the cell.
  • Cells have not always existed. The very first cell had to form from non-living chemistry on the early Earth, roughly 3.5–4 billion years ago.
  • That was a unique series of events that we do not see repeating today.
Cell
The smallest unit of life that can sustain itself — capable of metabolism, growth and reproduction on its own.
Unit of life
The idea that all living things are built from cells, and that the cell is the smallest thing that counts as alive.
Origin of cells
How the first living cells arose from non-living matter on the early Earth, a one-off event around 3.5–4 billion years ago.
Why 'self-sustaining' is the key word: A single organelle (such as a mitochondrion) or a virus is not the unit of life — neither can survive and reproduce on its own.

Only a whole cell has everything needed to keep itself going, so the cell is the smallest self-sustaining unit of life.

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The big idea: Something is living only if it carries out all the functions of life itself. A cell can; a virus cannot.

The points to remember

  • Living things carry out the functions of life: metabolism, growth, reproduction, response, homeostasis, nutrition and excretion.
  • A cell does all of them on its own, so the cell is the smallest unit of self-sustaining life.
  • A non-living thing may do one: a crystal grows, a flame uses oxygen. It never does all of them.
  • A virus is not a cell: a protein coat around DNA or RNA, with no cytoplasm and no ribosomes.
  • It has no metabolism of its own and is copied only inside a host cell, using the host's enzymes and ribosomes.
  • Outside a host, a virus does nothing at all, so viruses are considered non-living.
Remember it as: Alive = does every function of life by itself.
A bacterial cell with its cell membrane, cytoplasm, ribosomes and DNA labelled, beside a virus drawn as a protein coat around DNA or RNA, with no cytoplasm and no ribosomesA bacterial cell with its cell membrane, cytoplasm, ribosomes and DNA labelled, beside a virus drawn as a protein coat around DNA or RNA, with no cytoplasm and no ribosomes
The cell has everything it needs to run itself; the virus has only genes in a coat.
Real example: a virus as crystals: In 1935 Wendell Stanley purified tobacco mosaic virus into needle-shaped crystals, as you can with salt. Put back on tobacco leaves, the crystals still infected the plants. No living cell can be crystallised and come back like that.

When you give reasons, keep to what the virus cannot do for itself.

Reasons that do not count: "Viruses are very small" and "viruses cause disease" are not reasons: some bacteria are tiny and many cause disease, and they are alive.

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How it could be asked: No paper has asked this yet. The likely shape is a short Paper 2 question: outline why viruses are considered non-living, or distinguish a cell from a virus.
IB-style questionOutline[3 marks]

Outline the reasons that viruses are considered to be non-living.

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what is meant by the cell being the 'unit of life'. [1 mark]

Related Biology HL Topics

Continue learning with these related topics from the same unit:

1.1.1Water as the medium for life1.1.2Hydrogen bonds from the polar covalent bonds in water1.1.3Cohesion of water and its consequences for organisms1.1.4Adhesion of water to polar or charged materials
View all Biology HL topics
Improve your exam techniqueCommand terms, paper structure, and mark-scheme tips for Biology HL
Previous1.3.1Conditions on early Earth and the pre-biotic formation of carbon compoundsNextThe challenge of explaining the spontaneous origin of cells1.3.3

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