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NotesBiology HLTopic 4.5Consequences of removal of most but not all epigenetic tags from the ovum and sperm
Back to Biology HL Topics
4.5.93 min read

Consequences of removal of most but not all epigenetic tags from the ovum and sperm (Biology HL)

IB Biology · Unit 4

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Contents

  1. 1Most tags removed, some kept
  2. 2Why the father matters
  3. 3Exam-style question (step by step)
The big idea: When sperm and eggs form, most epigenetic tags are removed, but some stay. The tags that stay can make a gene's expression depend on which parent it came from.
Sperm and egg with most tags removed and a few kept; a liger with strong growth tags from its lion father, and a tigon whose lioness mother's tags hold growth back
Tags kept in gametes explain ligers and tigons.

The points to remember

  • Removing most tags lets the zygote start with an almost clean pattern of expression.
  • A few tags stay on some genes in the sperm or the egg.
  • So for these genes, expression depends on whether the copy came from the father or the mother.
  • This explains why ligers and tigons differ, though both are lion-tiger hybrids.
Remember it as: Lion father: liger. Lion mother: tigon.

Real example: ligers and tigons. A liger has a lion father and a tiger mother and grows much larger than either parent. A tigon has a tiger father and a lion mother and is no larger than its parents.

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Why the father matters: Ligers and tigons have the same two species as parents, so the difference must come from which tags each parent passes on.
LigerTigon
FatherLionTiger
MotherTigerLion
Tags kept from the fatherFavour growth stronglyFavour growth weakly
Tags kept from the motherHold growth back weaklyHold growth back strongly
SizeMuch larger than both parentsNo larger than its parents
Genes the same, tags different: Both hybrids get one set of lion genes and one set of tiger genes. Only the tags kept in the sperm and egg differ, so the phenotype differs.

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How it is asked: 1A items asking why ligers and tigons differ in size, and short written answers outlining the role of tags kept in the gametes.
IB-style questionOutline[3 marks]

Outline the epigenetic origin of the difference in size between ligers and tigons.

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what happens to most epigenetic tags when sperm and eggs are formed. [1 mark]

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