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NotesBiology HLTopic 4.4Roles of mitosis and meiosis in eukaryotes
Back to Biology HL Topics
4.4.43 min read

Roles of mitosis and meiosis in eukaryotes (Biology HL)

IB Biology · Unit 4

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Contents

  1. 1Roles of mitosis and meiosis at Higher Level
  2. 2Nucleus first
  3. 3Mitosis or meiosis
  4. 4Exam-style question (step by step)
Roles of mitosis and meiosis at Higher Level: The same statement as SL. At HL a four-mark 'distinguish between mitosis and meiosis' is a favourite Paper 2 opener.

Practise this as you read

  • State why the nucleus divides before the cell.
  • Distinguish between mitosis and meiosis.

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The big idea: In eukaryotes the nucleus divides before the cell does, so that no daughter cell is left anucleate (without a nucleus).
A parent cell: splitting it first would leave one daughter without a nucleus, so the nucleus divides first and then the cell
Nuclear division comes before cell division.

The points to remember

  • The nucleus holds the cell's genes, which control the cell's activities.
  • An anucleate cell cannot make new proteins for long and can never divide.
  • So nuclear division (mitosis or meiosis) comes first.
  • Then cytokinesis splits the cytoplasm between the new nuclei.
Remember it as: Divide the nucleus, then the cell.

Real example: phloem sieve tubes. The sieve tube cells of phloem lose their nucleus as they mature and can never divide again. A companion cell beside each one keeps its nucleus and supports it.

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Two kinds of nuclear division: Mitosis keeps the chromosome number and the genome the same. Meiosis halves the chromosome number and makes every cell genetically different.
Mitosis: a human cell with 46 chromosomes gives two cells with 46. Meiosis: it gives four cells with 23Mitosis: a human cell with 46 chromosomes gives two cells with 46. Meiosis: it gives four cells with 23
Human cells: 46 chromosomes; gametes: 23.
MitosisMeiosis
Chromosome numberKept the sameHalved
Genome of daughter cellsIdentical to the parentDifferent: genetic diversity
Daughter cellsTwoFour
RolesGrowth, repair, replacement, asexual reproductionMaking gametes for sexual reproduction
Why halve the number?: At fertilisation two gametes fuse. If they were not haploid, the chromosome number would double in every generation.
How it is asked: A Paper 2 'distinguish between mitosis and meiosis', a 1B 'distinguish between the cells produced', or a 1A item on what each division does to the chromosome number.
IB-style questionDistinguish[4 marks]

Distinguish between cell division by mitosis and by meiosis in eukaryotes.

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the term for a cell that has no nucleus. [1 mark]

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4.1.1DNA replication as production of exact copies of DNA with identical base sequences4.1.2Semi-conservative nature of DNA replication and role of complementary base pairing4.1.3Role of helicase and DNA polymerase in DNA replication4.1.4Polymerase chain reaction and gel electrophoresis as tools for amplifying and separating DNA
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Improve your exam techniqueCommand terms, paper structure, and mark-scheme tips for Biology HL
Previous4.4.3Equal and unequal cytokinesisNextDNA replication as a prerequisite for both mitosis and meiosis4.4.5

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