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NotesBiology HLTopic 4.4Cell proliferation for growth, cell replacement and tissue repair
Back to Biology HL Topics
4.4.123 min read

Cell proliferation for growth, cell replacement and tissue repair (Biology HL)

IB Biology · Unit 4

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Contents

  1. 1Why cells proliferate
  2. 2Three jobs, one process
  3. 3Exam-style question (step by step)
The big idea: Cell proliferation is a rapid increase in cell number by repeated cell division. Organisms use it to grow, to replace cells and to repair damage.
Four panels: a root tip with a meristem of small dividing cells, an embryo dividing from 1 to 8 cells, skin cells dividing at the base, and cells closing a cut
Proliferation: growth, replacement and repair.

The points to remember

  • Plant growth: cells in meristems (at root and shoot tips) keep dividing.
  • Animal growth: an early embryo divides again and again, with little growth between divisions.
  • Replacement: cells at the base of the skin divide all the time to replace cells lost at the surface.
  • Repair: after a wound, cells at its edges divide faster until the gap is closed.
Remember it as: Grow, replace, repair: all by dividing.

Real example: new skin. The outer layer of human skin is replaced roughly every four to six weeks, by cells dividing at its base and moving up to the surface.

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Three jobs, one process: The same process, mitosis followed by cytokinesis, does all three jobs; what differs is where and why it happens.
JobWhereWhat happens
Growth (plants)Meristems at root and shoot tipsCells divide, then grow and specialise
Growth (animals)Early embryoThe zygote divides into a ball of cells
ReplacementBase of the skinNew cells replace those lost at the surface
RepairEdges of a woundCells divide faster until the gap closes
Controlled, not random: Proliferation speeds up when it is needed and stops when it is not, for example once a wound has closed. The cell cycle and its controls (4.4.13 and 4.4.15) make this possible.

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How it is asked: A short answer on why cells divide in a named tissue, or a 1A item matching an example (meristem, embryo, skin, wound) to growth, replacement or repair.
IB-style questionOutline[3 marks]

Outline three different roles of cell proliferation in multicellular organisms, with an example of each.

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the term for a rapid increase in the number of cells by repeated cell division. [1 mark]

Related Biology HL Topics

Continue learning with these related topics from the same unit:

4.1.1DNA replication as production of exact copies of DNA with identical base sequences4.1.2Semi-conservative nature of DNA replication and role of complementary base pairing4.1.3Role of helicase and DNA polymerase in DNA replication4.1.4Polymerase chain reaction and gel electrophoresis as tools for amplifying and separating DNA
View all Biology HL topics
Improve your exam techniqueCommand terms, paper structure, and mark-scheme tips for Biology HL
Previous4.4.11Meiosis as a source of variationNextPhases of the cell cycle4.4.13

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