Back to Topic 3.7 — Defence against infectious disease
3.7.2Biology SL12 flashcards

Blood clotting and sealing wounds

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Card 1 of 123.7.2
3.7.2
Question

What is a blood clot?

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All 12 Flashcards — Blood clotting and sealing wounds

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Card 1definition

Question

What is a blood clot?

Answer

A plug of trapped blood cells held together by a mesh of **fibrin** fibres, which seals a damaged blood vessel.

Card 2concept

Question

What two jobs does a blood clot do?

Answer

It **stops blood loss** AND acts as a **barrier that keeps pathogens out** of the wound.

Card 3concept

Question

What causes a blood clot to form?

Answer

A **cut / damaged blood vessel** — its exposed surface activates platelets, which start the cascade.

Card 4concept

Question

What is the role of platelets in clotting?

Answer

They **stick** to the wound, **clump** together and **release clotting factors** that start the cascade.

Card 5definition

Question

What are clotting factors?

Answer

Chemicals released at a wound that **switch on** the cascade of reactions leading to a clot.

Card 6concept

Question

Which enzyme converts fibrinogen into fibrin?

Answer

**Thrombin** — it turns soluble fibrinogen into insoluble fibrin.

Card 7concept

Question

What is the difference between fibrinogen and fibrin?

Answer

**Fibrinogen** is **soluble** (dissolved in plasma); **fibrin** is **insoluble** and forms the fibre mesh of the clot.

Card 8concept

Question

What happens to prothrombin during clotting?

Answer

Clotting factors convert inactive **prothrombin** into the active enzyme **thrombin**.

Card 9concept

Question

What does the fibrin mesh do?

Answer

It **traps platelets and red blood cells**, forming the clot that dries into a **scab**.

Card 10concept

Question

Put the clotting cascade in order.

Answer

Cut vessel → platelets stick / release clotting factors → thrombin formed → fibrinogen → fibrin mesh → clot / scab.

Card 11concept

Question

Why does clotting only happen at a wound?

Answer

It is triggered by a **damaged vessel surface**; clots in healthy vessels could block blood flow, so 'no damage → no clot'.

Card 12concept

Question

How does a clot help prevent infection?

Answer

The clot / scab **seals the cut**, forming a **physical barrier** so pathogens cannot enter the tissues.

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IB Biology Blood clotting and sealing wounds Flashcards | 3.7.2 | Aimnova | Aimnova