Back to Topic 2.5 — Cell specialization
2.5.3Biology SL12 flashcards

Stem cells and potency

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Card 1 of 122.5.3
2.5.3
Question

What is a stem cell?

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All 12 Flashcards — Stem cells and potency

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Card 1definition

Question

What is a stem cell?

Answer

An **unspecialized** cell that can **self-renew** (keep dividing) and **differentiate** into specialized cell types.

Card 2concept

Question

What are the two defining properties of a stem cell?

Answer

**Self-renewal** (divides to make more stem cells) and **differentiation** (becomes specialized cells). Both are needed.

Card 3definition

Question

Define potency.

Answer

A measure of **how many different cell types** a stem cell can differentiate into.

Card 4concept

Question

What does totipotent mean, and give an example?

Answer

Can become **any cell type plus the placenta**. Example: the **zygote** / very early embryo.

Card 5concept

Question

What does pluripotent mean, and give an example?

Answer

Can become **any cell type of the body** (but not the placenta). Example: **embryonic stem cells**.

Card 6concept

Question

What does multipotent mean, and give an example?

Answer

Can become a **limited family of related** cell types. Example: **blood-forming cells in red bone marrow**.

Card 7concept

Question

What does unipotent mean?

Answer

Can become **only one** cell type.

Card 8concept

Question

What is the key difference between totipotent and pluripotent cells?

Answer

**Totipotent** cells can also form the **placenta**; **pluripotent** cells cannot.

Card 9concept

Question

How does potency change as cells develop?

Answer

Potency **decreases** (and specialization increases) as cells differentiate — adult stem cells are usually only multipotent or unipotent.

Card 10definition

Question

What is a stem-cell niche?

Answer

The **location in the body** where a particular stem cell is found (e.g. red bone marrow for blood-forming stem cells).

Card 11concept

Question

Classify a blood-forming stem cell by potency and niche.

Answer

**Multipotent** (forms the family of blood cells); niche = the **red bone marrow**.

Card 12concept

Question

Where are pluripotent stem cells found in a developing organism?

Answer

In the **early embryo** — they are the **embryonic stem cells**.

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