Unit 4: Continuity and Change

Topic 4.5: Gene Expression (HL) Questions

Practice 20 exam-style questions for IB Biology Topic 4.5. Review the question stems below, then unlock the full Question Bank to access markschemes, model answers, and AI grading.

1Define2 marks
Aimnova practice
Define the term transcription factor.
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2Identify1 mark
Which list contains only environmental factors known to alter epigenetic marks?
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3Identify1 mark
What kind of molecule is a transcription factor?
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4Identify1 mark
Which change is an epigenetic change rather than a mutation?
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5State1 mark
Aimnova practice
State the stage of gene expression at which transcription factors act to control whether a gene is expressed.
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6Define1 mark
Aimnova practice
Define the term epigenetic change.
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7Identify1 mark
At which stage is gene expression mainly controlled in a eukaryotic cell?
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8State1 mark
Aimnova practice
State the two processes that, together, make up the expression of a gene.
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9Identify1 mark
Which statement best describes an epigenetic change?
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10State1 mark
Aimnova practice
State what is meant by the term epigenetics.
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11State1 mark
Aimnova practice
State what is meant by an epigenetic mark.
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12Identify1 mark
What does it mean to say that a gene is 'expressed'?
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13Identify1 mark
Which change to a gene is normally reversible?
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14State1 mark
Aimnova practice
Expression of a gene is often measured from the amount of mRNA it produces. State the relationship between the amount of mRNA from a gene and how strongly that gene is expressed.
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15Identify1 mark
A change to a cell switches a gene off but leaves the DNA base sequence exactly as it was. What kind of change is this?
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16Identify1 mark
Which statement about epigenetic marks such as DNA methylation is correct?
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17Identify1 mark
A gene produces 60 units of mRNA in liver cells and 4 units of mRNA in skin cells. Both cell types contain the gene. What is the best conclusion?
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18Identify1 mark
The diagram shows the same stretch of DNA in two states. In the lower panel the gene is OFF. Which features of the lower panel explain why no mRNA is made? [Diagram: bio-gene-regulation]
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19Explain4 marks
Aimnova practice
Every cell in a multicellular organism is produced by mitosis from a single zygote, so all the cells contain identical DNA. Explain how cells with identical DNA can develop into different cell types with different structures and functions.
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20Identify1 mark
A mutation can change a protein's structure, but an epigenetic change does not. Why?
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