Unit 4: Continuity and Change
Topic 4.3: Mutation and Gene Editing Questions
Practice 20 exam-style questions for IB Biology Topic 4.3. Review the question stems below, then unlock the full Question Bank to access markschemes, model answers, and AI grading.
1Identify1 mark
How does a new allele of a gene first arise?
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Which stage of DNA profiling uses the polymerase chain reaction (PCR)?
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State which stage of DNA profiling is carried out by the polymerase chain reaction (PCR).
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How many copies of chromosome 21 are present in the body cells of a person with Down syndrome?
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State the amino acid change that occurs in the haemoglobin chain of a person with sickle-cell anaemia.
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In which type of gene mutation is one base swapped for a different base, leaving the total number of bases unchanged?
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State the meiotic error responsible for producing a gamete with an abnormal number of chromosomes.
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A mutation occurs in one of the cells listed below.
In which cell could the mutation be passed on to the person's children?
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Which enzyme JOINS a gene into a plasmid vector when making a genetically modified bacterium?
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Which of the following is a mutagen?
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What is meant by non-disjunction during meiosis?
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Which statement is a correct general feature of a mutation?
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State what is meant by the term mutation.
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State the type of cell in which a mutation must occur for it to be inherited by a person's offspring.
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Which statement best describes a germline mutation?
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Which protein is directly affected by the mutation that causes sickle-cell anaemia, and what is its normal job?
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What is the main purpose of the polymerase chain reaction in DNA profiling?
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Which amino acid change occurs in the haemoglobin chain of a person with sickle-cell anaemia?
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What type of mutation in the haemoglobin gene causes sickle-cell anaemia?
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During the denaturation step of PCR the DNA is heated to about 95 °C.
What does this achieve?
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