Unit 4: Continuity and Change

Topic 4.1: DNA Replication Questions

Practice 20 exam-style questions for IB Biology Topic 4.1. Review the question stems below, then unlock the full Question Bank to access markschemes, model answers, and AI grading.

1Distinguish2 marks
Aimnova practice
Distinguish between a gene and the genome of an organism.
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2Identify1 mark
Which conclusion did Meselson and Stahl reach from their density-labelling experiment?
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3Identify1 mark
What is the term for the whole of the genetic information of an organism?
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4Outline3 marks
Aimnova practice
Modern genetics often refers to the complete genetic information of an organism. State the term used for the whole of an organism's genetic information, and outline how it relates to genes and chromosomes.
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5State1 mark
Aimnova practice
State the conclusion Meselson and Stahl reached about how DNA is replicated.
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6Identify1 mark
What does it mean to say that DNA replication is semi-conservative?
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7State1 mark
Aimnova practice
State the term used for the whole of the genetic information of an organism.
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8Identify1 mark
Which sequence shows the three steps of one PCR cycle in the correct order?
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9Identify1 mark
Which bonds does helicase break to separate the two strands of DNA during replication?
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10State1 mark
Aimnova practice
State one reason why the enzyme Taq polymerase is suitable for use in the polymerase chain reaction (PCR).
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11Identify1 mark
Which enzyme unwinds and unzips the DNA double helix at the start of replication?
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12State1 mark
Aimnova practice
State the role of DNA polymerase in DNA replication.
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13Identify1 mark
During semi-conservative replication, what is the role of each parental (old) strand?
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14Identify1 mark
What is the main purpose of the polymerase chain reaction (PCR)?
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15Identify1 mark
By complementary base pairing, which nucleotide will DNA polymerase add opposite a guanine (G) on the template strand?
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16Identify1 mark
What happens during the annealing step of a PCR cycle, carried out at about 55 °C?
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17Identify1 mark
In which direction does DNA polymerase build each new strand?
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18Identify1 mark
An exam asks you to state the role of DNA polymerase. Which answer scores the mark?
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19Identify1 mark
Which row correctly pairs each enzyme with the bond it acts on during replication?
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20Identify1 mark
Why is the heat-stable enzyme Taq polymerase used in PCR rather than an ordinary DNA polymerase?
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