Unit 3: Interaction and Interdependence

Topic 3.5: Neural Signalling Questions

Practice 20 exam-style questions for IB Biology Topic 3.5. Review the question stems below, then unlock the full Question Bank to access markschemes, model answers, and AI grading.

1State1 mark
State where depolarization occurs along a myelinated axon during an action potential.
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2Identify1 mark
Which sensory receptor type detects the temperature of a hot drink touching the lips?
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3Identify3 marks
In a pain reflex arc, identify the receptor and the effector, and state where the synapses between the neurons are located.
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4Identify1 mark
What is the approximate value of the resting potential of a neuron, and is the inside positive or negative relative to the outside?
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5State1 mark
State the two components of the central nervous system.
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6Identify1 mark
Which two structures make up the central nervous system?
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7Identify1 mark
In which region does chemical transmission of a signal between two neurons most likely occur?
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8Identify1 mark
Which statement correctly describes the function of a sensory neuron?
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9State1 mark
State the directions in which sodium ions and potassium ions are moved by the sodium-potassium pump as it establishes the resting potential.
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10State1 mark
State where the synapses between the sensory neuron and the relay neuron of a reflex arc are located.
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11Calculate1 mark
2026
Calculate the total synaptic delay in the reflex arc.
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12Identify1 mark
Which ion enters the presynaptic neuron and triggers synaptic vesicles to fuse with the membrane?
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13Identify1 mark
A weak stimulus is applied to a neuron but no action potential is recorded. Which term best explains why nothing fired?
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14Identify1 mark
Which ion movements by the sodium-potassium pump establish the resting potential of a neuron?
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15Identify1 mark
What is the approximate resting potential of a neuron, and is the inside of the axon positive or negative?
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16Identify1 mark
On a diagram of a myelinated motor neuron, where does depolarization occur during an action potential?
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17State1 mark
State the name of the structure at which a chemical signal is passed from one neuron to the next.
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18State1 mark
State which ion moves into the axon during depolarisation, and the direction in which it moves.
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19Draw1 mark
2026
Draw a graph of membrane potential against time during an action potential.
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20Identify1 mark
In a pain (withdrawal) reflex arc, which structure acts as the receptor?
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