Unit 1: Unity and Diversity

Topic 1.2: Nucleic Acids Questions

Practice 20 exam-style questions for IB Biology Topic 1.2. Review the question stems below, then unlock the full Question Bank to access markschemes, model answers, and AI grading.

1Identify1 mark
Which molecule acts as the long-term genetic material stored in the cells of an oak tree?
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2Identify1 mark
In a DNA double helix, which components of the two strands are directly joined to each other by hydrogen bonds?
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3State1 mark
State the name of the monomer from which a DNA molecule is built.
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4State2 marks
A short single strand of DNA has the base sequence T–A–C–G–G–A. State the base sequence of the complementary strand that pairs with it.
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5Outline2 marks
Outline the feature of DNA that gives it the capacity to store a very large amount of information.
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6Distinguish2 marks
Distinguish between a gene and a genome.
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7Outline2 marks
Outline the meaning of complementary base pairing in a molecule of DNA.
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8Identify1 mark
What does whole genome sequencing of an organism involve?
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9Identify1 mark
A short single strand of nucleic acid is found to contain the base uracil. Which type of nucleic acid must this strand be, and why?
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10Identify1 mark
The diagram shows a single nucleotide. Which three components does every nucleotide contain? [Diagram: bio-dna-nucleotide {"type":"DNA"}]
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11Identify1 mark
Which feature of a DNA molecule gives it the capacity to store a very large amount of genetic information?
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12Identify1 mark
What molecules make up the backbone that runs along the outside of each DNA strand?
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13Define1 mark
Define the term genome.
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14State1 mark
2026
State the name of the protein around which DNA is wound in a eukaryotic nucleus.
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15Identify1 mark
Watson and Crick published a model of DNA in 1953. What overall structural feature did their model first reveal?
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16Outline1 mark
In a plant or animal chromosome, what is the role of histone proteins?
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17Identify1 mark
Which pair of base pairings correctly describes complementary base pairing in a DNA double helix?
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18Identify1 mark
A pentose sugar is extracted from a nucleotide and shown to be deoxyribose. From which nucleic acid did this nucleotide come?
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19Identify1 mark
Which statement correctly describes the genome of an organism?
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20Calculate1 mark
2026
Calculate the percentage of guanine.
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